NEWS

ORGANOID AND SPHEROIDS SELECT BIO CONFERENCE
June, 2023
Magdalena gave a keynote presentation on our work on regenerative potential of MSC in intestinal epithelium after chemotherapy-mediated damage.

AIMS
June, 2023
Celebration of the new department at the institute retreat.

NEW PAPER IS OUT
May, 2023
The paper were we demonstrate that treatment with MSCs may have unwanted proinflammatory effect in metabolic OA. Here we also show that for this type of OA, MSC-derived EVs might potentially be a better therapeutic option.
This work was a great collaborative effort with the labs of Harrie Weinans and Niels Eijkelkamp. Thank you all for your efforts and congratulations to the first author Kelly Warmink!

FIRST ORGANOID NL SYMPOSIUM
March, 2023
It has been a pleasure to share our work at the first OrganoidNL meeting. It has been a very interactive day full of interesting science.

KEYSTONE 2023 CONFERENCE ON ORGANOIDS AS MODELS OF DEVELOPMENT AND DISEASE
February, 2023
Magdalena gave a talk on the new co-culture model of MSC and intestinal organoids we have recently generated. Using this model it is possible to study the molecular mechanism of MSC-mediated regeneration of intestinal epithelium after chemotherapy-mediated damage.

NEW PAPER PUBLISHED
January, 2023
This review is a result of a fruitful collaboration with Tina Vermonden and Olivier de Jong labs. We discuss the current status and the future perspective on the use of MSC-derived extracellular vesicles as a therapeutic in cartilage regeneration.
Congratulations to the talented first author Sanne van de Looij!

OUR NEW PAPER PUBLISHED
December, 2022
Our new review on the role of extracellular vesicles in lysosomal storage disorders is out. Congratulations to the first author of this work, Vivian! Check here the video, where Vivian explains the content of the manuscript.

NLSEV 2022
November 2022
Suzy gave a talk on the regenerative potential of MSC-EVs in ALS motor neurons. The project we do in collaboration with Prof. Jeroen Pasterkamp lab.

LORENOWICZ LAB AT BPRC
November 2022
Lorenowicz lab has moved from Regenerative Medicine Center in Utrecht to Biomedical Primate Research Center in Rijswijk, where Magdalena became a head of a new department of Advanced In vitro Model Systems (AIMS). We are excited about the new opportunities this change will bring.

VIVIAN HAS GRADUATED!
Decemeber 2021
On 16th of December Vivian Hegeman has received her Master of Science diploma. Magdalena recorded a video with a laudation for Vivian, as unfortunately it was still not possible to do it in person. Congratulations Vivian! We are looking forward to when our paths will cross again!

NLSEV ANNUAL CONFERENCE
November 2021
Suzy presented a poster on MSC-EVs regenerative potential in ALS motor neurons during NLSEV 2021 conference. It was good to see everyone in person again and discuss exciting EV science.

MAGDALENA JOINS EDITORIAL BOARD OF EVCNA
October 2020
Magdalena accepted an invitation to join the Editorial Board of newly established journal of Extracellular Vesicles and Circulating Nucleic Acids. EVCNA provides an online platform for the sharing of research data, new methodology, reviews and commentaries in the areas of extracellular vesicles and circulating nucleic acids and their therapeutic use.

DORIAN HAS GRADUATED!
September 2020
On 28th of September Dorian Luijkx has received his Master of Science diploma. Magdalena has written the laudatory speech for this occasion, which was read by Dorian's study coordinator. Congratulations Dorian! Good luck with your PhD endeavour in Maastricht!

OUR NEW PAPER PUBLISHED
April 2020
Our review discussing the challenges and opportunities in use of MSC-EVs as a therapeutic in tissue repair is out! Congratulations to Suzy, who put in a lot of work to make it happen!

WELCOME BAHAR!
November 2019
Bahar joined the lab to work on the role of MSC and their secretome in the repair of intestinal tissue.

GRANT AWARDED
July 2019
Magdalena received a grant from KIKA Foundation to study the role of MSC and their secretome in the repair of intestinal tissue.
![IMG_5926[1].JPG](https://static.wixstatic.com/media/fcfaaa_fa8a5433541e4ac0adc650950546692e~mv2_d_4032_3024_s_4_2.jpg/v1/fill/w_460,h_345,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/IMG_5926%5B1%5D_JPG.jpg)
VISIT IN ANCONA
June 2019
Magdalena visited the Polytechnic University of Marche in Ancona, Italy, to give a seminar on our recent finding regarding the role of MSC and their secretome in tissue repair.

NAS 2019
May 2019
We had a great time at the 8th Nordic Autophagy Society conference in Utrecht, where Suzy presented poster on MSC-EVs role in the regulation of autophagy in cartilage.

WELCOME SUZY!
April 2019
Suzy joined the lab to work on the molecular mechanism underlying the anti-inflammatory and regenerative properties of MSC-derived extracellular vesicles in cartilage repair.

LOTTE HAS GRADUATED!
February 2019
On 11th of February Lotte van den Bent has received her Master of Science diploma. Magdalena was happy to give a laudatory speech for this occasion. Congratulation Lotte! Good luck with your PhD!

VISIT PROF. EDIT BUZAS
January 2019
Professor Edit Buzas from Semmelweis University, Budapest has visited the lab. She gave an overview of her work on the extracellular vesicles within the regenerative medicine seminar series. Prof. Buzas also gave an interactive masterclass on recent developments in EV field.
![IMG_4867[1].JPG](https://static.wixstatic.com/media/fcfaaa_d1b475f45ab149dba5b8de4d57de0a2d~mv2_d_4032_3024_s_4_2.jpg/v1/fill/w_460,h_345,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/IMG_4867%5B1%5D_JPG.jpg)
VISIT IN BELGRADE
December 2018
Magdalena has visited Belgrade to present our recent data on role of MSC-EV in cartilage regeneration on the Fifth Symposium of regenerative medicine “Stem cells – a vision beyond borders”, Belgrade, Serbia.

GRANT AWARDED
November 2018
Magdalena was awarded grant from Dutch Arthritis Foundation to study the molecular mechanism of how MSC-EVs regulate cartilage regeneration.

VISIT DR. MICHIEL PEGTEL
October 2018
Dr. Michiel Pegtel visits the lab to give an overview of the recent developments of his research on extracellular vesicles. It has been a very well received seminar and fruitful discussion. We look forward to future collaboration.

RALUCA TUTUIANU VISITED THE LAB
August 2018
Raluca Tutuianu from the Laboratory of Mesenchymal Stromal Progenitor Cells Therapy at "Nicolae Simionescu" Institute of Cellular Biology and Pathology in Bucharest visited the lab to learn everything about MSC-derived EVs. We look forward to future collaboration.

GRANT AWARDED
June 2018
Magdalena was awarded K.F. Hein Fonds grant for the work aiming to understand the communication between MSC and injured intestinal epithelium.

OUR NEW PAPER PUBLISHED
January 2018
Our paper on the role of MSC-EVs in cartilage regeneration is published in Theranostics.

GRANT AWARDED
July 2017
Magdalena in collaboration with Dr. Lucienne Vonk from Department of Orthopaedics was awarded Translationeel Adult Stamcelonderzoek (TAS) Game changer grant from ZonMW for continuation of the work on the role of MSC-EVs in cartilage regeneration.