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NEWS

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ORGANOID NL 2024

April, 2024

Kari-Pekka presented a poster on our work on regenerative properties of MSCs in intestinal epithelium at a very dynamic second edition of OrganoidNL meeting in Amsterdam.

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WELCOME GUNJAN

April, 2024

Gunjan joined the lab to embark on the PhD jurney and study the role of EVs in virus-induced degeneration.

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PAPER PUBLISHED

April, 2024

Our paper describing a development of a new co-culture model of small intestine organoids and MSCs to study the regenerative properties of MSCs on chemotherapy-induced damage in intestine was jsut published in the Stem Cell Research and Therapy.

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GRANT AWARDED

April, 2024

Together with our collaborators at Erasmus MC we will be testing alternatives for chemotherapy.

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FIRST SYMPOSIUM ON 'EXTRACELLULAR VESICLES IN NERVOUS SYSTEM'

December, 2023

Suzy presented our collaborative work with Jeroen Pasterkamp's lab on regenerative properties of MSC-EVs in ALS motor neurons.

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MAGDALENA JOINS NLSEV BOARD

March, 2024

Magdalena join the board of NLSEV and is happy to help in further shaping this rapidly growing society.

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GRANT AWARDED

January, 2024

We happy to be part of the Long-COVID consortium, which aims to gain insights into the mechanism of this disease and to discover diagnostic and therapeutic tools for this condition.

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ORGANOID AND SPHEROIDS SELECT BIO CONFERENCE

June, 2023

Magdalena gave a keynote presentation on our work on regenerative potential of MSC in intestinal epithelium after chemotherapy-mediated damage.

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AIMS

June, 2023

Celebration of the new department at the institute retreat.

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WELCOME KARI-PEKKA

September, 2023

Kari-Pekka joined the lab to support us as a Lab Manager.

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GRANT AWARDED

NOVEMBER, 2023

We are a part of ISIDORe JRA programme, where we will be designing advanced in vitro models to study virus mediated degeneration.

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NLSEV ANNUAL CONFERENCE

NOVEMBER, 2023

It was again a pleasure to participate in annual NLSEV conference, this time in Rotterdam. As usual the meeting was full of lively discussions and exchange of ideas.

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NEW PAPER IS OUT

May, 2023

The paper were we demonstrate that treatment with MSCs may have unwanted proinflammatory effect in metabolic OA. Here we also show that for this type of OA, MSC-derived EVs might potentially be a better therapeutic option.
This work was a great collaborative effort with the labs of Harrie Weinans and Niels Eijkelkamp. Thank you all for your efforts and congratulations to the first author Kelly Warmink!

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FIRST ORGANOID NL SYMPOSIUM

March, 2023

It has been a pleasure to share our work at the first OrganoidNL meeting. It has been a very interactive day full of interesting science.

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KEYSTONE 2023 CONFERENCE ON ORGANOIDS AS MODELS OF DEVELOPMENT AND DISEASE

February, 2023

Magdalena gave a talk on the new co-culture model of MSC and intestinal organoids we have recently generated. Using this model it is possible to study the molecular mechanism of MSC-mediated regeneration of intestinal epithelium after chemotherapy-mediated damage.

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NEW PAPER PUBLISHED

January, 2023

This review is a result of a fruitful collaboration with Tina Vermonden and Olivier de Jong labs. We discuss the current status and the future perspective on the use of MSC-derived extracellular vesicles as a therapeutic in cartilage regeneration.
Congratulations to the talented first author Sanne van de Looij!

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OUR NEW PAPER PUBLISHED

December, 2022

Our new review on the role of extracellular vesicles in lysosomal storage disorders is out. Congratulations to the first author of this work, Vivian! Check here the video, where Vivian explains the content of the manuscript.

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NLSEV 2022

November 2022

Suzy gave a talk on the regenerative potential of MSC-EVs in ALS motor neurons. The project we do in collaboration with Prof. Jeroen Pasterkamp lab.

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LORENOWICZ LAB AT BPRC

November 2022

Lorenowicz lab has moved from Regenerative Medicine Center in Utrecht to Biomedical Primate Research Center in Rijswijk, where Magdalena became a head of a new department of Advanced In vitro Model Systems (AIMS). We are excited about the new opportunities this change will bring.

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VIVIAN HAS GRADUATED!

Decemeber 2021

On 16th of December Vivian Hegeman has received her Master of Science diploma. Magdalena recorded a video with a laudation for Vivian, as unfortunately it was still not possible to do it in person. Congratulations Vivian! We are looking forward to when our paths will cross again!

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NLSEV ANNUAL CONFERENCE

November  2021

Suzy presented a poster on MSC-EVs regenerative potential in ALS motor neurons during NLSEV 2021 conference. It was good to see everyone in person again and discuss exciting EV science.

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MAGDALENA JOINS EDITORIAL BOARD OF EVCNA

October 2020

Magdalena accepted an invitation to join the Editorial Board of newly established journal of Extracellular Vesicles and Circulating Nucleic Acids. EVCNA provides an online platform for the sharing of research data, new methodology, reviews and commentaries in the areas of extracellular vesicles and circulating nucleic acids and their therapeutic use.

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DORIAN HAS GRADUATED!

September 2020

On 28th of September Dorian Luijkx has received his Master of Science diploma. Magdalena has written the laudatory speech for this occasion, which was read by Dorian's study coordinator.  Congratulations Dorian! Good luck with your PhD endeavour in Maastricht!

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OUR NEW PAPER PUBLISHED

April 2020

Our review discussing the challenges and opportunities in use of MSC-EVs as a therapeutic in tissue repair is out! Congratulations to Suzy, who put in a lot of work to make it happen!

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WELCOME BAHAR!

November 2019

Bahar joined the lab to work on the role of MSC and their secretome in the repair of intestinal tissue.

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GRANT AWARDED

July 2019

Magdalena received a grant from KIKA Foundation to study the role of MSC and their secretome in the repair of intestinal tissue.

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VISIT IN ANCONA

June 2019

Magdalena visited the Polytechnic University of Marche in Ancona, Italy, to give a seminar on our recent finding regarding the role of MSC and their secretome in tissue repair.

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NAS 2019

May 2019

We had a great time at the 8th Nordic Autophagy Society conference in Utrecht, where Suzy presented poster on MSC-EVs role in the regulation of autophagy in cartilage.

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WELCOME SUZY!

April 2019

Suzy joined the lab to work on the molecular mechanism underlying the anti-inflammatory and regenerative properties of MSC-derived extracellular vesicles in cartilage repair.

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LOTTE HAS GRADUATED!

February 2019

On 11th of February Lotte van den Bent has received her Master of Science diploma. Magdalena was happy to give a laudatory speech for this occasion. Congratulation Lotte! Good luck with your PhD!

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VISIT PROF. EDIT BUZAS

January 2019

Professor Edit Buzas from Semmelweis University, Budapest has visited the lab. She gave an overview of her work on the extracellular vesicles within the regenerative medicine seminar series. Prof. Buzas also gave an interactive masterclass on recent developments in EV field.

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VISIT IN BELGRADE

December 2018

Magdalena has visited Belgrade to present our recent data on role of MSC-EV in cartilage regeneration on the Fifth Symposium of regenerative medicine “Stem cells – a vision beyond   borders”, Belgrade, Serbia.

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GRANT AWARDED

November 2018

Magdalena was awarded grant from Dutch Arthritis Foundation to study the molecular mechanism of how MSC-EVs regulate  cartilage regeneration.

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VISIT DR. MICHIEL PEGTEL

October 2018

Dr. Michiel Pegtel visits the lab to give an overview of the recent developments of his research on extracellular vesicles. It has been a very well received seminar and fruitful discussion. We look forward to future collaboration.

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RALUCA TUTUIANU VISITED THE LAB

August 2018

Raluca Tutuianu from the Laboratory of Mesenchymal Stromal Progenitor Cells Therapy at "Nicolae Simionescu" Institute of Cellular Biology and Pathology in Bucharest visited the lab to learn everything about MSC-derived EVs. We look forward to future collaboration.

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GRANT AWARDED

June 2018

Magdalena was awarded K.F. Hein Fonds grant for the work aiming to understand the communication between MSC and injured intestinal epithelium.

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OUR NEW PAPER PUBLISHED

January 2018

Our paper on the role of MSC-EVs in cartilage regeneration is published in Theranostics.

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GRANT AWARDED

July 2017

Magdalena in collaboration with Dr. Lucienne Vonk from Department of Orthopaedics was awarded Translationeel Adult Stamcelonderzoek (TAS) Game changer grant from ZonMW for continuation of the work on the role of MSC-EVs in cartilage regeneration.

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